What to Know About St. Denis Medical Season 2
The feel-better comedy returns.

The doctors and nurses at St. Denis Medical are ready to see you now. NBC’s mockumentary hospital comedy returns for Season 2, and it promises to be funnier than ever.
Here’s everything you need to know about the new season of St. Denis Medical.
When does St. Denis Medical Season 2 premiere?
Season 2 of St. Denis Medical premieres Monday, Nov 3 at 8p ET/PT on NBC with back-to-back episodes.
How can I watch St. Denis Medical Season 2 on Peacock?
New episodes will stream next day on Peacock beginning Tuesday, Nov 4. Check out this guide on when NBC’s fall shows are coming to Peacock.
What is St. Denis Medical Season 2 about?
St. Denis Medical is a mockumentary about an underfunded, understaffed Oregon hospital where the dedicated doctors and nurses try their best to treat patients while maintaining their own sanity.
In Season 2, after receiving a large private donation, hospital administrator Joyce bites off more than she can chew, while her employees navigate staff shortages, office conflicts, and their own personal lives.
Who’s in the cast of St. Denis Medical?
The series regulars of St. Denis Medical are:
- Wendi Mclendon-Covey as Joyce
- David Alan Grier as Dr. Ron
- Allison Tolman as Alex
- Josh Lawson as Dr. Bruce
- Kahyun Kim as Serena
- Mekki Leeper as Matt
- Kaliko Kauahi as Val
Season 2 will welcome several new faces, including:
- Ariana Madix (Love Island USA, Love Island Games) as Dr. Emerson
- Kristen Schaal (Bob’s Burgers) as Ashley
- Lauren Weedman (Looking) as Pam
- Frankie Quiñones (This Fool) as Leslie
- Lauren Lapkus (Orange Is the New Black)
- Tim Baltz (The Righteous Gemstones)
- Jonah Beckett (The Sex Lives of College Girls) as Kyle
- Jeremiah Brown (Love Island USA) as Jeff
Is there a trailer for St. Denis Medical Season 2?
Yes! The official trailer teases the exciting guest stars who will be walking the halls of St. Denis Medical, as well as a new therapy horse (with some "unanticipated downsides”), hospital hijinks, and quirky patients.
Watch the official trailer for St. Denis Medical on YouTube.
Catch the Season 2 premiere of St. Denis Medical on Monday, Nov 3 at 8p ET/PT on NBC, and stream it next day on Peacock.
Stream the first season of St. Denis Medical on Peacock.